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Medicine Lake Volcano is a large shield volcano in northeastern California about 50 kilometers (30 mi) northeast of Mount Shasta. The volcano is located in a zone of east-west crustal extension east of the main axis of the Cascade Volcanic Arc and the Cascade Range. The 1-kilometer (0.6 mi) thick shield is 35 km (22 mi) from east to west and 45 to 50 km (28 to 31 mi) from north to south, and covers more than 2,000 km2 (770 sq mi). The underlying rock has downwarped by 0.5 km (0.3 mi) under the center of the volcano. The volcano is primarily composed of basalt and basaltic andesite lava flows, and has a 7 km × 12 km (4.3 mi × 7.5 mi) caldera at the center.